Improving Diagnosis of Postmenopausal Bleeding

Plain-Language Summary
This study compared transvaginal ultrasound and outpatient hysteroscopy for postmenopausal women with abnormal uterine bleeding (AUB). Results showed that ultrasound alone may miss cancers, while hysteroscopy with biopsy detected all malignancies with high accuracy.

Key Takeaways:

• Ultrasound with a 4 mm cutoff may fail to identify endometrial cancer.

• Hysteroscopy with biopsy achieved 100% sensitivity for cancer detection.

• Outpatient hysteroscopy is simple, safe, and should be standard in postmenopausal AUB evaluation.

Citation:
Litta P, Merlin F, Saccardi C, et al. Role of hysteroscopy with endometrial biopsy to rule out endometria